Jada Pinkett Smith stars as Director of Nursing Christina Hawthorne, a passionate advocate for her patients who must balance the demands of being a widowed mother. When cutbacks close Richmond Trinity, Christina and several of her fellow doctors and nurses join the struggling James River Hospital. She defies enormous odds to rescue a heroin-addicted mother, confronts angry protestors to save a death row patient, and takes on the entire review board to keep the hospital open. On the home front, Christina also fights to raise her rapidly maturing daughter, while deciding if Christina herself is ready for a closer relationship with the Chief of Surgery Dr. Wakefield